Tissue Lysates
Reaction Biology Corp BRD4 Full Length protein, human recombinant, 100 μg, N-terminal His-tag, C-terminal StrepII-tag
The REACTION BIOLOGY CORP BRD4 Full Length protein is a human recombinant bromodomain-containing protein 4 that plays a significant role in transcriptional regulation and cell cycle progression. This protein, produced in Sf9 insect cells, features N-terminal His and C-terminal StrepII tags, enabling specific binding to ε-N-acetyllysine residues. Mainly recognized for its function in chromatin regulation, cancer research, and inflammation studies, BRD4 is also an atypical kinase that phosphorylates RNA Polymerase II.
- Produced in Sf9 insect cells
- Active transcriptional regulator
- Contains two bromodomains
- Has a molecular weight of 156.5 kDa
- Tagged with N-terminal His and C-terminal StrepII
- Purity exceeds 85% by SDS-PAGE
- Stored at -70°C or -80°C
- Functionally important for BET bromodomain studies
Medchemexpress LLC Kelch-like ECH-associated protein 1 | >90.0% | 100 UG
Recombinant human Kelch-like ECH-associated protein 1 (KEAP1) produced in Sf9 insect cells and supplied as a 0.22 μm filtered solution in 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5. The protein contains N-terminal His and GST tags, is supplied at laboratory scale (100 μg), and is intended for biochemical and binding assays. Store frozen and avoid repeated freeze-thaw cycles; buffer exchange is recommended for SPR applications.
- Recombinant human protein expressed in Sf9 insect cells.
- N-terminal His and GST tags facilitate purification and detection.
- Supplied as a filtered solution in Tris/NaCl/glycerol buffer.
- Observed molecular weight ~93-109 kDa by SDS-PAGE.
- Stable when stored at -80 °C; avoid repeated freeze-thaw cycles.
Cayman Chemical SynthetIc ScoulerIn 1mg
A benzylisoquinoline alkaloid with diverse biological activities; selectively binds to the dopamine D1 and D2 receptors (Kis = 22 and 214 nM, respectively) over 5-HT1A and 5-HT2A receptor subtypes in HEK293 cells at 10 µM; inhibits proliferation in a panel of leukemia cell lines (IC50s = 2.7-6.5 µM); inhibits methamphetamine-induced conditioned place preference in mice at 5 mg/kg
Meso Scale Discovery U-PLEX Rat PYY total ASY
The Meso Scale Discovery U-PLEX Rat PYY Total Assay Kit is a multiplex immunoassay that measures total PYY in rat samples The kit uses electrochemiluminescence detection technology and provides reagents for testing up to 1536 samples in a 96-well plate format The assay has a typical sensitivity of 0 3 pg/mL and a broad dynamic range from 0 3-10 000 pg/mL The kit includes a plate coated with capture antibodies detection antibodies labeled with electrochemiluminescent labels calibrators controls assay and wash buffers and an MSD instrument for detection The assay requires a low sample volume of 50 L and has high specificity with minimal cross-reactivity